| 1 | Spider-Man: Brand New Day | 2026-07-29 | $225M | $936.77M | 4.16 |
| 2 | Spider-Man: No Way Home | 2021-12-15 | $200M | $864.8M | 4.32 |
| 3 | Spider-Man: Across the Spider-Verse | 2023-05-31 | $100M | $398.94M | 3.99 |
| 4 | Spider-Man: Far From Home | 2019-06-28 | $160M | $391.36M | 2.45 |
| 5 | Spider-Man: Homecoming | 2017-07-05 | $175M | $349.97M | 2.00 |
| 6 | Project Hail Mary | 2026-03-15 | $200M | $344.05M | 1.72 |
| 7 | Venom: Let There Be Carnage | 2021-09-30 | $110M | $225.09M | 2.05 |
| 8 | Venom | 2018-09-28 | $116M | $223.51M | 1.93 |
| 9 | Spider-Man: Into the Spider-Verse | 2018-12-06 | $90M | $193.67M | 2.15 |
| 10 | Venom: The Last Dance | 2024-10-22 | $120M | $148.26M | 1.24 |
| 11 | Ghostbusters | 2016-07-14 | $144M | $131.68M | 0.91 |
| 12 | Little Women | 2019-12-25 | $40M | $108.1M | 2.70 |
| 13 | The Post | 2017-12-22 | $50M | $82.51M | 1.65 |
| 14 | Challengers | 2024-04-18 | $55M | $52.02M | 0.95 |
| 15 | Molly's Game | 2017-12-07 | $30M | $28.78M | 0.96 |